Following up on the post below, Allen Glosson writes in the comments:
For a somewhat more pointed view about reforming the FDA, you might also see http://www.stopfda.org, in particular the essay about "Consumer Rape".Incredible, and damning.
The story I like the most about the FDA involves Beta Blockers. Back in 1984, Dr. Kessler proudly announced that the FDA had approved Beta Blockers to treat high blood pressure and that the approval would save 17000 lives each year. What he didn't tell us was that Beta Blockers had been approved in Europe in the mid 1970s and approval was sought with the FDA back in 1977. The FDA took 7 years to approve a drug which had already been shown effective in European markets. Thus, the FDA had willfully and deliberately allowed over 100K people to die needlessly while they dotted i's and crossed t's in the approval process.
Do we still believe that the FDA saves lives? I for one, do not.